Victor refuses to make a second monster, but is convinced when the monster assures Victor that he will leave Europe and move to South America. Victor agrees to begin work on a second creation and makes plans to go to England and Scotland, with Henry Clerval, to begin his secret work. Before he leaves Geneva, Victor agrees to marry Elizabeth immediately upon his return from the British Isles. Victor takes up residence in the Orkney Islands, off the coast of Scotland. Victor destroys his project and goes out to sea to dispose of the remains. The monster vows revenge on Victor not upholding his end of their bargain.
While at sea, Victor's boat is blown off course by a sudden storm, and he ends up in Ireland. Henry Clerval's body has washed up on the shores of Ireland, and Victor is set to stand trial for murder. Fortunately, Mr. Kirwin, a local magistrate, intercedes on Victor's behalf and pleads his case before a court, which then finds Victor innocent of the crime. Victor is miserable knowing he has caused the deaths of so many, but recovers enough to finalize the plans for his marriage to Elizabeth.
With a wedding date set, Victor torments himself with the thought of the monster's threat to be with him on his wedding night. The wedding goes off as planned. While Victor makes sure he covers all possible entrances that the monster could use to get into the wedding chamber, the monster steals into Elizabeth's room and strangles her.
Victor now wants revenge and chases the monster through Europe and Russia. Victor nearly catches the monster near the Arctic Circle when Robert Walton discovers him. Victor, now near death, is taken aboard Walton's ship to recover from exhaustion and exposure.
The monster appears out of the mists and ice to visit his foe one last time. The monster enters the cabin of the ship and tells Walton his side of the story. Victor dies, and the monster tells Walton that he will burn his own funeral pyre. The monster then disappears in the waves and darkness, never to be seen again.