The Doctor's response to Darnay's declaration of love for Lucie indicates that the Evrémonde family ties may yet have the power to disrupt his life. Additionally, Dickens has dropped hints that Darnay or his family has something to do with the Doctor's secret. The Doctor has looked at Darnay with dislike, distrust, and fear on occasion, even though Darnay has done nothing to cause offense. Similarly, the secret smile that the Marquis wore when questioning Darnay about Doctor Manette strongly suggests that he knows something about the Doctor's history.
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